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About the company
Aprea Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on precision oncology through synthetic lethality. The Company's advanced synthetic lethality product candidate is ATRN-119, a clinical-stage small molecule inhibitor of ataxia telangiectasia and Rad3-related (ATR) a kinase that plays a critical role in DNA damage response (DDR). ATR and Checkpoint Kinase 1 are critical DDR kinases that prevent the collapse of replication forks into DNA double-strand breaks. It has completed all IND enabling studies for its oral, small molecule WEE1 inhibitor, APR-1051, and received United States Food and Drug Administration (FDA) clearance of its IND. It has an early-stage program that is in the lead optimization stage, for an undisclosed DDR target. The Company is evaluating potential combination opportunities within its pipeline, including research on the combination of ATRN-119 and APR-1051 that is supported by a Phase II SBIR grant from the National Cancer Institute.
- Revenue in USD (TTM)1.28m
- Net income in USD-12.93m
- Incorporated2019
- Employees7.00
- LocationAprea Therapeutics Inc3805 OLD EASTON ROADDOYLESTOWN 18902United StatesUSA
- Phone+1 (617) 463-9385
- Fax+1 (302) 655-5049
- Websitehttps://www.aprea.com/
Peer analysis
- Key Information
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- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Kazia Therapeutics Ltd (ADR) | 15.22k | -13.80m | 12.69m | 12.00 | -- | 1.20 | -- | 834.08 | -0.8373 | -0.8373 | 0.0008 | 0.3565 | 0.0007 | -- | 73.97 | -- | -63.98 | -46.35 | -82.39 | -54.75 | -- | -- | -90,714.45 | -497.17 | -- | -- | 0.1297 | -- | 979.43 | -28.31 | 18.19 | -- | -- | -- |
| Aspira Women's Health Inc | 8.92m | -15.95m | 13.04m | 64.00 | -- | -- | -- | 1.46 | -1.45 | -1.45 | 0.801 | -0.2892 | 1.53 | 15.11 | 5.79 | 139,421.90 | -273.16 | -110.58 | -3,758.30 | -151.88 | 57.84 | 45.23 | -178.80 | -334.08 | 0.5542 | -17,354.00 | -- | -- | 11.85 | 24.56 | 44.15 | -- | -26.65 | -- |
| Alterola Biotech Inc | 0.00 | -2.06m | 13.14m | 1.00 | -- | -- | -- | -- | -0.0017 | -0.0017 | 0.00 | -0.001 | 0.00 | -- | -- | 0.00 | -32.46 | -- | -46.53 | -- | -- | -- | -- | -- | 0.0073 | -- | -- | -- | -- | -- | -14.64 | -- | -- | -- |
| Cadrenal Therapeutics Inc | 0.00 | -6.24m | 13.21m | 4.00 | -- | 3.31 | -- | -- | -5.88 | -5.88 | 0.00 | 3.74 | 0.00 | -- | -- | 0.00 | -138.35 | -- | -173.80 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -24.47 | -- | -- | -- |
| Pharmacyte Biotech Inc | 0.00 | 4.50m | 13.52m | 2.00 | 3.48 | 0.2847 | 3.01 | -- | 0.5058 | 0.5058 | 0.00 | 6.87 | 0.00 | -- | -- | 0.00 | 35.90 | -7.42 | 38.19 | -7.68 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -299.38 | -- | -- | -- |
| Cingulate Inc | 0.00 | -19.10m | 13.70m | 13.00 | -- | 1.14 | -- | -- | -141.60 | -141.60 | 0.00 | 3.95 | 0.00 | -- | -- | 0.00 | -368.85 | -- | -- | -- | -- | -- | -- | -- | -- | -47.38 | 0.0042 | -- | -- | -- | -33.14 | -- | -- | -- |
| Edesa Biotech Inc | 0.00 | -6.93m | 13.96m | 16.00 | -- | 4.87 | -- | -- | -2.21 | -2.21 | 0.00 | 0.8829 | 0.00 | -- | -- | 0.00 | -94.60 | -- | -128.81 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 52.28 | -- | -- | -- |
| Aprea Therapeutics Inc | 1.28m | -12.93m | 14.13m | 7.00 | -- | 0.5526 | -- | 11.08 | -3.03 | -3.03 | 0.2898 | 4.95 | 0.0435 | -- | -- | 182,241.40 | -44.09 | -68.66 | -50.11 | -77.19 | -- | -- | -1,013.41 | -42,112.84 | -- | -- | 0.00 | -- | -- | -- | 87.32 | -- | 90.61 | -- |
| Lyra Therapeutics Inc | 1.82m | -101.39m | 14.31m | 87.00 | -- | 0.4619 | -- | 7.86 | -1.61 | -1.61 | 0.0294 | 0.4733 | 0.0165 | -- | -- | 20,681.82 | -92.07 | -58.01 | -108.51 | -68.69 | -- | -- | -5,570.88 | -6,235.31 | -- | -- | 0.00 | -- | 14.31 | 4.60 | -13.39 | -- | 95.14 | -- |
| Imunon Inc | 0.00 | -18.08m | 14.40m | 33.00 | -- | 2.51 | -- | -- | -1.92 | -1.92 | 0.00 | 0.398 | 0.00 | -- | -- | 0.00 | -94.15 | -50.18 | -132.90 | -60.27 | -- | -- | -- | -5,725.88 | -- | -- | 0.00 | -- | -100.00 | -- | 45.64 | -- | 26.69 | -- |
| Inhibitor Therapeutics Inc | 0.00 | -3.02m | 14.61m | 3.00 | -- | 3.53 | -- | -- | -0.0175 | -0.0175 | 0.00 | 0.024 | 0.00 | -- | -- | 0.00 | -34.83 | 27.48 | -34.99 | 32.70 | -- | -- | -- | -- | -- | -- | 0.00 | 0.00 | -- | -- | -125.39 | -- | -- | -- |
| Protext Mobility Inc | 750.00 | -2.21m | 14.95m | 4.00 | -- | -- | -- | 19,926.77 | -0.4692 | -0.4692 | 0.00001 | -0.0102 | 0.0405 | -- | -- | -- | -9,400.97 | -1,587.94 | -- | -- | 86.67 | -530.19 | -232,392.00 | -17,498.83 | 0.0002 | -1.36 | -- | -- | -93.98 | -63.09 | 27.35 | -- | -- | -- |
| Apollomics Inc | 0.00 | -57.11m | 15.62m | 45.00 | -- | 0.7505 | -- | -- | -0.568 | -0.568 | 0.00 | 0.1892 | 0.00 | -- | -- | 0.00 | -107.81 | -- | -144.29 | -- | -- | -- | -- | -- | -- | -- | 0.185 | -- | -- | -- | 28.33 | -- | -- | -- |
| Holder | Shares | % Held |
|---|---|---|
| AIGH Capital Management LLCas of 30 Jun 2024 | 539.30k | 9.93% |
| Sio Capital Management LLCas of 31 Mar 2024 | 276.60k | 5.09% |
| Sphera Funds Management Ltd.as of 31 Mar 2024 | 270.00k | 4.97% |
| Nantahala Capital Management LLCas of 31 Mar 2024 | 205.76k | 3.79% |
| DAFNA Capital Management LLCas of 31 Mar 2024 | 137.17k | 2.53% |
| The Vanguard Group, Inc.as of 31 Mar 2024 | 115.98k | 2.14% |
| Geode Capital Management LLCas of 30 Jun 2024 | 35.67k | 0.66% |
| Morgan Stanley & Co. LLCas of 31 Mar 2024 | 26.74k | 0.49% |
| Hightower Advisors LLCas of 31 Mar 2024 | 13.86k | 0.26% |
| Dimensional Fund Advisors LPas of 30 Jun 2024 | 9.67k | 0.18% |
